New findings in mice could inform novel treatment strategies for diseases that cause blindness — ScienceDaily

Dovie Salais

New insight on how people with retinal degenerative disease can maintain their night vision for a relatively long period of time has been published today in the open-access eLife journal.

The study in mice suggests that second-order neurons in the retina, which relay visual signals to the retinal ganglion cells that project into the brain, maintain their activity in response to photoreceptor degeneration to resist visual decline — a process known as homeostatic plasticity. Rod photoreceptors are the cells responsible for the most sensitive aspects of our vision, allowing us to see at night, but can be lost during retinal degenerative disease.

The new findings pave the way for further research to understand how our eyes and other sensory systems respond and adapt to potentially compromising changes throughout life.

“Neuronal plasticity of the inner retina has previously been seen to occur in response to photoreceptor degeneration, but this process has

Read More

Dodgers ace Clayton Kershaw’s status unclear after Game 2 scratch due to back spasms

Dovie Salais

ARLINGTON, Texas (AP) — Clayton Kershaw was scratched Tuesday from his start for the Los Angeles Dodgers in Game 2 of the NL Championship Series due to back spasms, though manager Dave Roberts said the likelihood is very good their ace lefty will pitch in the series.

The three-time NL Cy Young Award winner initially felt spasms after a bullpen session Saturday, three days after he went six innings to win Game 2 of the National League Division Series against San Diego. Roberts said Kershaw has felt better each day since but wasn’t ready to make the scheduled start against the Atlanta Braves.

“Sunday, played some catch and just started to dissipate, got a little bit better. And then yesterday, a little bit better, even more,” Roberts said. “And then today just woke up and felt that it just wasn’t quite where he wanted to be, we wanted it to

Read More

Selena Gomez on Overcoming Her Pandemic Depression | Video

Dovie Salais

As part of Rare Beauty’s Rare Impact Fund, which seeks to raise $100 million for mental health services for underserved communities over the next 10 years, Selena Gomez sat down for a virtual discussion with Vivek Murthy, MD, physician and former surgeon general under the Obama Administration. During the interview, Dr. Vivek addressed the negative impacts of the COVID-19 pandemic on people’s mental health, and Selena opened up about her personal experiences with depression as a result of the shelter-in-place orders.

“My job is a lot of travel, connecting with people, making people happy and that makes me happy, so it has been a struggle,” Gomez said, explaining that the huge shift in her extroverted lifestyle forced her to reflect on her relationships and her emotions. “In the beginning I couldn’t deal with it that well. I kind of went into a bit of a depression. Then I started going

Read More

Severe morning sickness raises depression risk

Dovie Salais

Severe morning sickness increases the risk of depression both during and after pregnancy, new research has found.

Severe morning sickness, known as hyperemesis gravidarum (HG), is a debilitating condition that affects around 1-2 per cent of pregnant women in the UK. Far more serious than ‘normal’ morning sickness, it is one of the most common reasons for hospitalisation during pregnancy and can continue right up until birth. Women can be bed-bound for weeks on end,suffer dehydrationand weight loss and are often unable to work or care for other children they have.

The study, by researchers from Imperial College London and Imperial College Healthcare NHS Trust, found that nearly half of women with HGsuffered antenatal depression and nearly 30 per cent had postnatal depression. In women without the condition, just six per cent experienced antenatal depression and seven per cent suffered postnatal depression.

Read More

LI company’s diabetes drug recalled due to cancer concerns

Dovie Salais

Some batches of a diabetes drug sold by a Farmingdale company are being recalled after they were found to contain higher-than-normal levels of a known carcinogen, officials said.

The metformin hydrochloride extended-release tablets are being voluntarily recalled by manufacturer Marksans Pharma Ltd. of Mumbai, India. The generic prescription drug was found to contain more than the acceptable level of nitrosodimethylamine, which can cause cancer, according to the officials.

The tablets are sold to U.S. pharmacies via Time-Cap Labs Inc., located across from Farmingdale’s Republic Airport. The local company, which also goes by Time Cap Labs, is a subsidiary of Marksans, Meena Rani, vice president of regulatory affairs and compliance, said Monday night.

The recalled tablets, which are 500 and 750 milligrams each, are used to treat type 2 diabetes. The tablets are white or off-white with 101 or 102 stamped on the side. Seventy-six lots are affected.

More information about

Read More

Selena Gomez Says She Went ‘Into a Bit of a Depression’ at the Start of Quarantine

Dovie Salais

From ELLE

Over the weekend, Selena Gomez did an Instagram Live with Dr. Vivek Murthy, the surgeon general under President Barack Obama, to discuss chronic loneliness as part of her Rare Beauty’s Mental Health Social Summit for World Mental Health Day. Gomez was candid talking to Dr. Murthy about her own difficulty coping with quarantine and the isolation it has imposed on everyone for the last six-plus months, saying she went through “a bit of a depression” initially.

“I’d say I’m a big-time extrovert so I get that it’s a bit harder,” Gomez started after asking Dr. Murthy about whether the experience is different for extroverted versus introverted people. “Or at least I feel that because my other [introverted] friend feels what you’re explaining as peaceful and having time to process. and I’m like, ‘I need to talk to someone! I need to do something!’ So I definitely get that.”

Read More

Type 1 diabetes could develop when babies are still in the WOMB

Dovie Salais


a close up of a hand holding a remote control: MailOnline logo


© Provided by Daily Mail
MailOnline logo

Type 1 diabetes may develop when babies are still in the womb, a study has found.

Previously experts thought that the condition only strikes when infants are older than six months.

But new research led by the University of Exeter found that the autoimmune disease – which occurs when the immune system attacks insulin-producing cells- can develop before infants are even born.

Experts said the breakthrough raises hope that scientists could find new treatments for type 1 diabetes.

Diabetes occurs when blood sugar levels rise to risky levels and can lead to fatal complications, including amputations, sight loss, kidney disease, stroke and heart disease.



a close up of a person holding a cell phone: Experts said the breakthrough raises hope that scientists could find new treatments for type 1 diabetes


© Provided by Daily Mail
Experts said the breakthrough raises hope that scientists could find new treatments for type 1 diabetes

WHAT IS TYPE 1 DIABETES?

Type 1 diabetes is an unpreventable autoimmune disease that usually develops in childhood,

Read More

Rheumatoid Arthritis Drugs Market to reach US$ 26,758.6 Mn by 2026

Dovie Salais

Albany, NY — (SBWIRE) — 10/13/2020 — The global rheumatoid arthritis drugs market was valued at US$ 19597.4 Mn in 2016. It is anticipated to expand at a stable CAGR of more than 2.5% between 2018 and 2026, according to a new report published by Transparency Market Research (TMR) titled “Rheumatoid Arthritis Drugs Market – Global Industry Analysis, Size, Share, Growth, Trends, and Forecast, 2018–2026”. Expansion of the global rheumatoid arthritis drugs market is due to strong research & development and increasing awareness regarding usage of biologic drugs for rheumatoid arthritis treatment during the forecast period. The rheumatoid arthritis drugs market in Asia Pacific is expanding with a high potential to grow, registering a CAGR of more than 3.0% due to the high prevalence of diseases, development in health care sector, and increased focus on research and developmental activities in the region.

Request a Sample of Rheumatoid Arthritis Drugs Market

Read More

Selena Gomez Reveals She ‘Went Into A Bit Of Depression’ During Lockdown

Dovie Salais

KEY POINTS

  • Selena Gomez said she faced mental health issues during the early days of the lockdown
  • The singer revealed she “went into a bit of depression” because she was used to traveling and connecting with people
  • Gomez recently received the coveted ARTS award during the 33rd annual Hispanic Heritage Awards

Selena Gomez has opened up about her mental health struggles during the lockdown, revealing that she “went into a bit of depression” during the early days of the coronavirus pandemic.

“In the beginning, I couldn’t deal with it that well. I kind of went into a bit of a depression,” Gomez told Dr. Vivek Murthy in a video posted on the Rare Beauty Instagram account.

During their conversation, the “Boyfriend” singer revealed that she found it difficult to cope during the lockdown because she is used to traveling a lot and connecting with people. She also finds joy in

Read More

Could an ‘invisible’ cell transplant treat diabetes?

Dovie Salais

Type 1 diabetes used to be a death sentence. After a diagnosis, patients were put on a starvation diet. The lucky ones would have a year or two to live. But, thanks to the discovery of insulin in the early 1920s, this is no longer the case.

We need insulin to regulate our blood sugar. After a meal, insulin helps our cells to use the sugar in our food. We use this sugar as fuel for energy – without insulin, sugar has nowhere to go. It stays in the bloodstream, and over time, damages blood vessels.

People with type 1 diabetes inject themselves with insulin to control their blood sugar level. However, while the treatment is a lifesaver, it can’t prevent people from developing diabetic complications. These conditions can be life limiting, so what if there was a treatment that was better than insulin injections?

Well, there might be, and

Read More